Article
Prevalence of RNA polymerase stalling at Escherichia coli promoters after open complex formation.
Molecular microbiology - 1 Apr 2008
Hatoum Asma, Roberts Jeffrey
Abstract excerpt
RNA polymerase (RNAP) trapped in intermediate stages of promoter escape, as well as RNAP paused at promoter-proximal sigma(70)-dependent pause sites, gives rise to stable, transcriptionally engaged stalled complexes that can limit promoter function and present potential sites for transcription regulation. To investigate the prevalence of such intermediates, we screened 118 Escherichia coli candidate promoters for...
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