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Article

Distinct functions of the RNA polymerase σ subunit region 3.2 in RNA priming and promoter escape.

Nucleic acids research - 1 Apr 2014

Pupov Danil, Kuzin Ivan, Bass Irina, Kulbachinskiy Andrey

Abstract excerpt

The σ subunit of bacterial RNA polymerase (RNAP) has been implicated in all steps of transcription initiation, including promoter recognition and opening, priming of RNA synthesis, abortive initiation and promoter escape. The post-promoter-recognition σ functions were proposed to depend on its conserved region σ3.2 that directly contacts promoter DNA immediately upstream of the RNAP active centre and occupies the...

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Identifiers

PMID: 24452800
DOI: 10.1093/nar/gkt1384
PMCID: PMC3985618

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Source receipt: pubmed, retrieved 7 Sept 2026.

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