Article
Long-Range Modulation of PAG1 Expression by 8q21 Allergy Risk Variants.
American journal of human genetics - 6 Aug 2015
Vicente Cristina T, Edwards Stacey L, Hillman Kristine M, Kaufmann Susanne, Mitchell Hayley, Bain Lisa, Glubb Dylan M, Lee Jason S, French Juliet D, Ferreira Manuel A R
Abstract excerpt
The gene(s) whose expression is regulated by allergy risk variants is unknown for many loci identified through genome-wide association studies. Addressing this knowledge gap might point to new therapeutic targets for allergic disease. The aim of this study was to identify the target gene(s) and the functional variant(s) underlying the association between rs7009110 on chromosome 8q21 and allergies. Eight genes are...
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