Article
Eleven loci with new reproducible genetic associations with allergic disease risk.
The Journal of allergy and clinical immunology - 1 Feb 2019
Ferreira Manuel A R, Vonk Judith M, Baurecht Hansjörg, Marenholz Ingo, Tian Chao, Hoffman Joshua D, Helmer Quinta, Tillander Annika, Ullemar Vilhelmina, Lu Yi, Rüschendorf Franz, Hinds David A, Hübner Norbert, Weidinger Stephan, Magnusson Patrik K E, Jorgenson Eric, Lee Young-Ae, Boomsma Dorret I, Karlsson Robert, Almqvist Catarina, Koppelman Gerard H, Paternoster Lavinia
Abstract excerpt
BACKGROUND: A recent genome-wide association study (GWAS) identified 99 loci that contain genetic risk variants shared between asthma, hay fever, and eczema. Many more risk loci shared between these common allergic diseases remain to be discovered, which could point to new therapeutic opportunities. OBJECTIVE: We sought to identify novel risk loci shared between asthma, hay fever, and eczema by applying a...
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