Article
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children.
PLoS genetics - 1 Aug 2009
Hancock Dana B, Romieu Isabelle, Shi Min, Sienra-Monge Juan-Jose, Wu Hao, Chiu Grace Y, Li Huiling, del Rio-Navarro Blanca Estela, Willis-Owen Saffron A G, Willis-Owens Saffron A G, Weiss Scott T, Raby Benjamin A, Gao Hong, Eng Celeste, Chapela Rocio, Burchard Esteban G, Tang Hua, Sullivan Patrick F, London Stephanie J
Abstract excerpt
Many candidate genes have been studied for asthma, but replication has varied. Novel candidate genes have been identified for various complex diseases using genome-wide association studies (GWASs). We conducted a GWAS in 492 Mexican children with asthma, predominantly atopic by skin prick test, and their parents using the Illumina HumanHap 550 K BeadChip to identify novel genetic variation for childhood asthma....
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