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Article

Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.

American journal of human genetics - 1 Sept 2009

Verlaan Dominique J, Berlivet Soizik, Hunninghake Gary M, Madore Anne-Marie, Larivière Mathieu, Moussette Sanny, Grundberg Elin, Kwan Tony, Ouimet Manon, Ge Bing, Hoberman Rose, Swiatek Marcin, Dias Joana, Lam Kevin C L, Koka Vonda, Harmsen Eef, Soto-Quiros Manuel, Avila Lydiana, Celedón Juan C, Weiss Scott T, Dewar Ken, Sinnett Daniel, Laprise Catherine, Raby Benjamin A, Pastinen Tomi, Naumova Anna K

Abstract excerpt

Common SNPs in the chromosome 17q12-q21 region alter the risk for asthma, type 1 diabetes, primary biliary cirrhosis, and Crohn disease. Previous reports by us and others have linked the disease-associated genetic variants with changes in expression of GSDMB and ORMDL3 transcripts in human lympho...

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Source

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Identifiers

PMID: 19732864
DOI: 10.1016/j.ajhg.2009.08.007
PMCID: PMC2771592

Genes

CTCF
GSDMB
ORMDL3
ZPBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19732864-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.PMID 19732864Read ↗

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