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Article

Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis.

The Journal of allergy and clinical immunology - 1 Mar 2016

Andiappan Anand Kumar, Sio Yang Yie, Lee Bernett, Suri Bani Kaur, Matta Sri Anusha, Lum Josephine, Foo Shihui, Koh Geraldine, Liu Jianjun, Zolezzi Francesca, Poidinger Michael, Wang De Yun, Rotzschke Olaf, Chew Fook Tim

Abstract excerpt

BACKGROUND: Allergic rhinitis (AR) and asthma are common allergic conditions with a shared genetic component to their cause. The 17q12-21 locus includes several genes that have been linked to asthma susceptibility, but the role of this locus in AR is unclear. Asthma and AR in adults of Chinese ethnicity in Singapore are predominately caused by sensitization against house dust mites with a nearly complete...

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Source

Identifiers

PMID: 26483175
DOI: 10.1016/j.jaci.2015.08.038

Genes

ORMDL3
GSDMB
ZPBP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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