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Article

The Influence of Oxygen on the Proliferative Capacity and Differentiation Potential of Lacrimal Gland-Derived Mesenchymal Stem Cells.

Investigative ophthalmology & visual science - 1 Jul 2015

Roth Mathias, Spaniol Kristina, Kordes Claus, Schwarz Silke, Mertsch Sonja, Häussinger Dieter, Rotter Nicole, Geerling Gerd, Schrader Stefan

Abstract excerpt

PURPOSE: The application of lacrimal gland-derived mesenchymal stem cells (LG-MSC) for the regeneration of lacrimal gland tissue could result in a novel therapy for dry-eye syndrome. To optimize the culture conditions, the purpose of this study was to evaluate the influence of low oxygen on phenotype, differentiation potential, proliferative, and regenerative capacity of murine LG-MSC. METHODS: Murine LG-MSC were...

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PMID: 26207311
DOI: 10.1167/iovs.14-15475

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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