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Article

Effect of three-dimensional culture and incubator gas concentration on phenotype and differentiation capability of human mesenchymal stem cells.

Journal of cellular biochemistry - 1 Feb 2011

Karlsen Tommy A, Mirtaheri Peyman, Shahdadfar Aboulghassem, Fløisand Yngvar, Brinchmann Jan E

Abstract excerpt

To obtain sufficient numbers of cells for tissue engineering applications, human bone marrow-derived mesenchymal stem cells (hBM-MSC) are commonly cultured as monolayers in incubators containing room air. In this study, we investigated whether three-dimensional (3D) culture conditions and incubator gas concentrations more similar to those observed in vivo impacted on cell expansion, differentiation capability, or...

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Identifiers

PMID: 21268090
DOI: 10.1002/jcb.22978

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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