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Human Lacrimal Gland Derived Mesenchymal Stem Cells – Isolation, Propagation, and Characterization

13 Jul 2023

Abstract excerpt

Purpose: The existing treatment options for dry eye disease (DED) due to lacrimal gland (LG) dysfunction are mainly palliative. Mesenchymal stem cells (MSCs) based therapies and 3D-LG organoids have been explored as a curative option for LG regeneration in animal models. Human LG epithelial cultures are previously established and, here, we aim to isolate and characterize the spindle-shaped cells obtained from...

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PMID: 37440263
DOI: 10.1167/iovs.64.10.12

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