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Article

The effects of low oxygen on self-renewal and differentiation of embryonic stem cells.

Current opinion in organ transplantation - 1 Dec 2009

Millman Jeffrey R, Tan Jit Hin, Colton Clark K

Abstract excerpt

PURPOSE OF REVIEW: To summarize recent reports on the effects of low oxygen on the undifferentiated phenotype and differentiation of embryonic stem cells (ESCs). RECENT FINDINGS: The oxygen level to which ESCs are exposed is an important environmental parameter. Under conditions maintaining the undifferentiated phenotype, low oxygen reduces spontaneous differentiation of human ESCs but reduces pluripotency gene...

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Source

Identifiers

PMID: 19779343
DOI: 10.1097/MOT.0b013e3283329d53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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