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Article

Effect of low oxygen tension on the biological characteristics of human bone marrow mesenchymal stem cells.

Cell stress & chaperones - 1 Nov 2016

Kim Dae Seong, Ko Young Jong, Lee Myoung Woo, Park Hyun Jin, Park Yoo Jin, Kim Dong-Ik, Sung Ki Woong, Koo Hong Hoe, Yoo Keon Hee

Abstract excerpt

Culture of mesenchymal stem cells (MSCs) under ambient conditions does not replicate the low oxygen environment of normal physiological or pathological states and can result in cellular impairment during culture. To overcome these limitations, we explored the effect of hypoxia (1 % O2) on the biological characteristics of MSCs over the course of different culture periods. The following biological characteristics...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27565660
DOI: 10.1007/s12192-016-0733-1
PMCID: PMC5083677

Genes

CCL2
CXCL10
CXCL9
CXCR4
KLF4
MSC
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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