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Article

Low atmospheric oxygen avoids maturation, senescence and cell death of murine mesencephalic neural precursors

26 Jan 2005

Abstract excerpt

The efficient generation of specific brain cells in vitro may serve as a source of cells for brain repair in several devastating neurological diseases. Production of dopaminergic neurons from precursor cells for transplantation in Parkinson's disease has become a major research goal. We found that murine mesencephalic neurospheres were viable and proliferated, preserved telomerase activity, pluripotency and...

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PMID: 15686473
DOI: 10.1111/j.1471-4159.2004.02893.x

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