Article
Genome-Wide Assessment of Differential DNA Methylation Associated with Autoantibody Production in Systemic Lupus Erythematosus.
PloS one - 1 Jan 2015
Chung Sharon A, Nititham Joanne, Elboudwarej Emon, Quach Hong L, Taylor Kimberly E, Barcellos Lisa F, Criswell Lindsey A
Abstract excerpt
Systemic lupus erythematosus (SLE) is characterized by the development of autoantibodies associated with specific clinical manifestations. Previous studies have shown an association between differential DNA methylation and SLE susceptibility, but have not investigated SLE-related autoantibodies. Our goal was to determine whether DNA methylation is associated with production of clinically relevant SLE-related...
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