Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneity

1 Jul 2018

Abstract excerpt

SLE is a complex autoimmune disease that results from the interplay of genetics, epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism that regulates gene expression and tissue differentiation. Among all the epigenetic modifications, DNA methylation perturbations have been the most widely studied in SLE. It mediates processes relevant to SLE, including lymphocyte development,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30094041
DOI: 10.1136/lupus-2018-000285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneityPMID 30094041Read ↗

DNA methylation in systemic lupus erythematosus.Semantic proximity Read ↗

Epigenetics in SLESemantic proximity Read ↗

DNA methylation changes on immune cells in Systemic Lupus ErythematosusSemantic proximity Read ↗

Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical PracticeSemantic proximity Read ↗

DNA methylation alterations in the pathogenesis of lupusSemantic proximity Read ↗

What can we learn from DNA methylation studies in lupus?Semantic proximity Read ↗

Epigenetic Alterations in Immune Cells of Systemic Lupus Erythematosus and Therapeutic Implications.Semantic proximity Read ↗

Region- and variance-based DNA methylation analyses reveal novel disease genes and pathways for systemic lupus erythematosusSemantic proximity Read ↗

Epigenetic Variability in Systemic Lupus Erythematosus: What We Learned from Genome-Wide DNA Methylation StudiesSemantic proximity Read ↗

The Lupus Epigenome Relates to Genetics, Transcription and Serological Profiles with Dependency on Molecular Subtypes and Informs Drug DiscoverySemantic proximity Read ↗

An updated review on abnormal epigenetic modifications in the pathogenesis of systemic lupus erythematosus.Semantic proximity Read ↗

DNA Methylation Profiling in Childhood-Onset Lupus Reveals Distinct Epigenetic Clusters and Suggests Epigenetic Drivers of Disease ActivitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.