Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing

26 Nov 2014

Abstract excerpt

We performed a high-resolution analysis of the biological characteristics of plasma DNA in systemic lupus erythematosus (SLE) patients using massively parallel genomic and methylomic sequencing. A number of plasma DNA abnormalities were found. First, aberrations in measured genomic representations (MGRs) were identified in the plasma DNA of SLE patients. The extent of the aberrations in MGRs correlated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Parvovirus B19 Infection Studies
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25427797
DOI: 10.1073/pnas.1421126111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencingPMID 25427797Read ↗

DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneitySemantic proximity Read ↗

Region- and variance-based DNA methylation analyses reveal novel disease genes and pathways for systemic lupus erythematosusSemantic proximity Read ↗

Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical PracticeSemantic proximity Read ↗

Systemic Lupus Erythematosus Patients with DNASE1L3·Deficiency Have a Distinctive and Specific Genic Circular DNA Profile in PlasmaSemantic proximity Read ↗

DNA Methylation Profiling in Childhood-Onset Lupus Reveals Distinct Epigenetic Clusters and Suggests Epigenetic Drivers of Disease ActivitySemantic proximity Read ↗

Jagged Ends on Multinucleosomal Cell-Free DNA Serve as a Biomarker for Nuclease Activity and Systemic Lupus ErythematosusSemantic proximity Read ↗

DNA methylation in systemic lupus erythematosus.Semantic proximity Read ↗

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosusSemantic proximity Read ↗

The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell ResolutionSemantic proximity Read ↗

Genome-Wide Assessment of Differential DNA Methylation Associated with Autoantibody Production in Systemic Lupus Erythematosus.Semantic proximity Read ↗

Genome-wide analysis of 5-hmC in the peripheral blood of systemic lupus erythematosus patients using an hMeDIP-chip.Semantic proximity Read ↗

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.