Article
DNA methylation in systemic lupus erythematosus.
Epigenomics - 1 Apr 2017
Hedrich Christian M, Mäbert Katrin, Rauen Thomas, Tsokos George C
Abstract excerpt
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease facilitated by aberrant immune responses directed against cells and tissues, resulting in inflammation and organ damage. In the majority of patients, genetic predisposition is accompanied by additional factors conferring disease expression. While the exact molecular mechanisms remain elusive, epigenetic alterations in immune cells have been...
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