Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical Practice

24 Apr 2018

Abstract excerpt

Differential DNA methylation has emerged as a critical feature of systemic lupus erythematosus (SLE). Genome-wide DNA methylation studies have revealed methylation patterns characteristic of SLE—in particular, robust hypomethylation of interferon-regulated genes is a prominent finding in all cells of the immune system studied to date. These patterns reliably distinguish individuals with SLE from healthy controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurogenetic and Muscular Disorders Research
Share to Pregnancy and preeclampsia studies
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29740453
DOI: 10.3389/fimmu.2018.00875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical PracticePMID 29740453Read ↗

DNA methylation in systemic lupus erythematosus.Semantic proximity Read ↗

DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneitySemantic proximity Read ↗

Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell PopulationsSemantic proximity Read ↗

Region- and variance-based DNA methylation analyses reveal novel disease genes and pathways for systemic lupus erythematosusSemantic proximity Read ↗

Epigenetic Alterations in Immune Cells of Systemic Lupus Erythematosus and Therapeutic Implications.Semantic proximity Read ↗

DNA methylation changes on immune cells in Systemic Lupus ErythematosusSemantic proximity Read ↗

Epigenetics in SLESemantic proximity Read ↗

Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon PathwaySemantic proximity Read ↗

Epigenetic mechanisms in lupusSemantic proximity Read ↗

DNA Methylation Profiling in Childhood-Onset Lupus Reveals Distinct Epigenetic Clusters and Suggests Epigenetic Drivers of Disease ActivitySemantic proximity Read ↗

DNA methylation alterations in the pathogenesis of lupusSemantic proximity Read ↗

An updated review on abnormal epigenetic modifications in the pathogenesis of systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.