Correlation between acute myeloid leukemia and IL-17A, IL-17F, and IL-23R gene polymorphism.

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Article

Correlation between acute myeloid leukemia and IL-17A, IL-17F, and IL-23R gene polymorphism.

International journal of clinical and experimental pathology - 1 Jan 2015

Zhu Biao, Zhang Jianbo, Wang Xiaodong, Chen Jiao, Li Chenglong

Abstract excerpt

Recent studies have shown that Th17 cells may be involved in the pathological process of acute myeloid leukemia. This CD4+ cell subgroup secretes highly homologous interleukin (IL)-17A and IL-17F, and also expresses IL-23 receptor (IL-23R) on the cell surface. Our study aims to investigate the relationship of IL-17A, IL-17F, and IL23R with disease susceptibility, and clarify the relationship between gene...

Topics

Adult
Aged
Aged, 80 and over
Enzyme-Linked Immunosorbent Assay
Female
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-17
Leukemia, Myeloid, Acute
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Real-Time Polymerase Chain Reaction

Receptors, Interleukin

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 26191290
PMCID: PMC4503161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26191290-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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