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Article

Involvement of IL17A, IL17F and IL23R Polymorphisms in Colorectal Cancer Therapy.

PloS one - 1 Jan 2015

Omrane Inés, Medimegh Imen, Baroudi Olfa, Ayari Hager, Bedhiafi Walid, Stambouli Nejla, Ferchichi Marwa, Kourda Nadia, Bignon Yves-Jean, Uhrhammer Nancy, Mezlini Amel, Bougatef Karim, Benammar-Elgaaied Amel

Abstract excerpt

IL23/IL17 pathway plays an important role in the development of inflammatory bowel diseases (IBD). In general, the genes encoding the cytokines are genetically polymorphic and polymorphisms in genes IL23R and IL17 have been proved to be associated with its susceptibility to inflammatory diseases as well as cancer including colorectal cancer. Moreover, it has been shown that these interleukins are involved in...

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Identifiers

PMID: 26083022
DOI: 10.1371/journal.pone.0128911
PMCID: PMC4470506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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