Article
IL-17A )rs2275913; G197A) gene polymorphism as predictor for disease severity and its correlation with IL-17 serum levels in COVID-19 patients.
The Egyptian journal of immunology - 1 Jul 2022
Rushdy Marwa, Elsayed Marwa S, Ahmed Rasha, Gaber Amr G, El-Asady Riham
Abstract excerpt
Severity of symptoms in COVID-19 has been shown to result from a cytokine storm. Interleukin (IL)-17 is one of these various cytokines, which results in a proinflammatory response, systemic inflammatory symptoms, inflammatory cell infiltration of lung tissue and thus leads to the massive lung pathology and multiorgan failure. Gene polymorphisms in the regulatory regions of cytokine-encoding genes affect the...
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