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Article

Potentially functional polymorphism in IL-23 receptor and risk of acute myeloid leukemia in a Chinese population.

PloS one - 1 Jan 2013

Qian Xifeng, Cao Songyu, Yang Guohua, Pan Yun, Yin Chenyu, Chen Xiang, Zhu Ying, Zhuang Yun, Shen Yunfeng, Hu Zhibin

Abstract excerpt

The interleukin-23 (IL-23) and its receptor (IL-23R) mediate the direct antitumor activities in human hematologic malignancies including pediatric acute leukemia. Two potentially functional genetic variants (IL-23R rs1884444 T>G and rs6682925 T>C) have been found to contribute to solid cancer susceptibility. In this study, we conducted a case-control study including 545 acute myeloid leukemia (AML) patients and...

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Identifiers

PMID: 23393581
DOI: 10.1371/journal.pone.0055473
PMCID: PMC3564797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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