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Article

IL-17F gene polymorphism is associated with susceptibility to acute myeloid leukemia.

Journal of cancer research and clinical oncology - 1 Sept 2014

Wróbel Tomasz, Gębura Katarzyna, Wysoczańska Barbara, Jaźwiec Bożena, Dobrzyńska Olga, Mazur Grzegorz, Kuliczkowski Kazimierz, Bogunia-Kubik Katarzyna

Abstract excerpt

PURPOSE: Recent studies have suggested that Th17 cells may play a role in the pathogenesis of acute myeloid leukemia (AML). This subset of CD4+ cells is characterized by interleukin (IL)-17A and IL-17F production, which share strong homology, and surface expression of the IL-23 receptor (IL-23R)....

Topics

Adult
Aged
Aged, 80 and over
Alleles
Female
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-17
Leukemia, Myeloid, Acute
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Receptors, Interleukin

Source

Open in PubMed Open full text

Identifiers

PMID: 24793548
DOI: 10.1007/s00432-014-1674-7
PMCID: PMC4131129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-24793548-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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