Article
Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis.
Human immunology - 1 Feb 2013
Saraiva Adriana Machado, Alves e Silva Micena Roberta Miranda, Correia Silva Jeane de Fátima, da Costa José Eustáquio, Gollob Kenneth John, Dutra Walderez Ornelas, Moreira Paula Rocha
Abstract excerpt
The IL23/Th17 axis plays an important role in the pathogenesis of cell-mediated tissue damage caused either by autoimmunity or immune responses against bacterial infection. Single nucleotide polymorphisms in the IL17A, IL17F and IL23R genes have been associated with several inflammatory diseases. However, these polymorphisms have not yet been studied in periodontitis. The aim of present study was to evaluate the...
Topics
- Adolescent
- Adult
- Alleles
- Brazil
- Female
- Genotype
- Humans
- Interleukin-17
- Male
- Middle Aged
- Periodontitis
