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Article

Genetic Analysis of IL-17 Gene Polymorphisms in Gout in a Male Chinese Han Population.

PloS one - 1 Jan 2016

Zhou Zheng, Li Xinde, Li Hua, Guo Mingzhen, Liu Shiguo, Li Changgui

Abstract excerpt

Interleukin (IL)-17 is a proinflammatory cytokine mainly secreted by activated T helper 17 cells and involved in inflammatory immune responses. This study aimed to investigate the association between IL-17 variants as well as serum IL-17 levels with gout in male Chinese Han individuals. A total of 1,101 male gout patients and 1,239 ethic-matched controls were enrolled. Genetic distributions of three variants...

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PMID: 26890073
DOI: 10.1371/journal.pone.0148082
PMCID: PMC4758639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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