Interleukin-17FT7488 allele is associated with a decreased risk of colorectal cancer and tumor progression.

doi:10.1016/j.gene.2015.02.014

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Article

Interleukin-17FT7488 allele is associated with a decreased risk of colorectal cancer and tumor progression.

Gene - 25 Apr 2015

Nemati Kazem, Golmoghaddam Hossein, Hosseini Seyed Vahid, Ghaderi Abbas, Doroudchi Mehrnoosh

Abstract excerpt

BACKGROUND: IL-17 family of cytokines and human IL-23R play important and sometimes contradictory roles in autoimmune and inflammatory diseases as well as human malignancies. Different alleles of this cytokine family may differentially affect IL-17 secretion. We sought to investigate the associat...

Topics

Base Sequence
Colorectal Neoplasms
Disease Progression
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Interleukin-17
Male
Middle Aged
Polymorphism, Single Nucleotide
Receptors, Interleukin
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 25680555
DOI: 10.1016/j.gene.2015.02.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25680555-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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