Article
Interleukin-17FT7488 allele is associated with a decreased risk of colorectal cancer and tumor progression.
Gene - 25 Apr 2015
Nemati Kazem, Golmoghaddam Hossein, Hosseini Seyed Vahid, Ghaderi Abbas, Doroudchi Mehrnoosh
Abstract excerpt
BACKGROUND: IL-17 family of cytokines and human IL-23R play important and sometimes contradictory roles in autoimmune and inflammatory diseases as well as human malignancies. Different alleles of this cytokine family may differentially affect IL-17 secretion. We sought to investigate the association of IL-17A, IL-17F and IL-23R gene polymorphisms with the susceptibility to colorectal cancer (CRC). METHODS: The...
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