Article
Impact of the IL-17F, IL-23 and IL-23R on susceptibility and phenotype of systemic lupus erythematosus.
Autoimmunity - 1 Sept 2016
Paradowska-Gorycka Agnieszka, Sowinska Anna, Stypinska Barbara, Grobelna Malwina Katarzyna, Walczyk Marcela, Olesinska Marzena, Piotrowski Piotr, Jagodziński Paweł Piotr
Abstract excerpt
Systemic lupus erythematosus (SLE) is a disease characterized by excessive proinflammatory cytokine production and damage to multiple organ systems. To investigate the potential association between cytokine gene polymorphisms and SLE, we performed a case-control study based on Polish population. SLE patients and controls, were examined for IL-23A rs11171806 G/A and IL-23R (rs1884444 G/T, rs10489629 G/A) by TaqMan...
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