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Article

Cell-selective labelling of proteomes in Drosophila melanogaster.

Nature communications - 3 Jul 2015

Erdmann Ines, Marter Kathrin, Kobler Oliver, Niehues Sven, Abele Julia, Müller Anke, Bussmann Julia, Storkebaum Erik, Ziv Tamar, Thomas Ulrich, Dieterich Daniela C

Abstract excerpt

The specification and adaptability of cells rely on changes in protein composition. Nonetheless, uncovering proteome dynamics with cell-type-specific resolution remains challenging. Here we introduce a strategy for cell-specific analysis of newly synthesized proteomes by combining targeted expression of a mutated methionyl-tRNA synthetase (MetRS) with bioorthogonal or fluorescent non-canonical amino-acid-tagging...

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Identifiers

PMID: 26138272
DOI: 10.1038/ncomms8521
PMCID: PMC4507001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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