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Article

Cell-specific proteomic analysis in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 2015

Yuet Kai P, Doma Meenakshi K, Ngo John T, Sweredoski Michael J, Graham Robert L J, Moradian Annie, Hess Sonja, Schuman Erin M, Sternberg Paul W, Tirrell David A

Abstract excerpt

Proteomic analysis of rare cells in heterogeneous environments presents difficult challenges. Systematic methods are needed to enrich, identify, and quantify proteins expressed in specific cells in complex biological systems including multicellular plants and animals. Here, we have engineered a Caenorhabditis elegans phenylalanyl-tRNA synthetase capable of tagging proteins with the reactive noncanonical amino...

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Identifiers

PMID: 25691744
DOI: 10.1073/pnas.1421567112
PMCID: PMC4352802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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