Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of Warfarin Genotype Polymorphisms in Patients with Mechanical Circulatory Support.

ASAIO journal (American Society for Artificial Internal Organs : 1992) - 1 Jan 2000

Awad Morcos, Czer Lawrence S C, Soliman Camelia, Mirocha James, Ruzza Andrea, Pinzas Joshua, Rihbany Kelsey, Chang David, Moriguchi Jaime, Ramzy Danny, Esmailian Fardad, Kobashigawa Jon, Arabia Francisco

Abstract excerpt

Polymorphisms for VKORC1 and CYP2C9 are associated with increased warfarin sensitivity. The prevalence of these polymorphisms in patients with mechanical circulatory support (MCS) is unknown. Polymorphisms for VKORC1 and CYP2C9 were determined in 65 patients undergoing MCS surgery. Postoperative warfarin dose, international normalized ratio (INR), and bleeding events were measured until discharge, 6 months, or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticoagulants
Share to Blood Coagulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

Share to International Normalized Ratio

Share to Polymorphism, Single Nucleotide

Share to Prevalence

Share to Vitamin K Epoxide Reductases

Share to Warfarin

Source

Open in PubMed Open full text

Identifiers

PMID: 26125664
DOI: 10.1097/MAT.0000000000000231
PMCID: PMC4487870

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of Warfarin Genotype Polymorphisms in Patients with Mechanical Circulatory Support.PMID 26125664Read ↗

Genetic variations of phenprocoumon metabolism in patients with ventricular assist devices.Semantic proximity Read ↗

Mechanical heart valve recipients: anticoagulation in patients with genetic variations of phenprocoumon metabolism.Semantic proximity Read ↗

Genotype-Guided Warfarin Dosing in Patients With Mechanical Valves: A Randomized Controlled Trial.Semantic proximity Read ↗

The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin.Semantic proximity Read ↗

Association between gene polymorphisms and initial warfarin therapy in patients after heart valve surgery.Semantic proximity Read ↗

Frequency Distribution of CYP2C9 and VKORC1 Mutations among Bulgarian Patients and their Importance for Anticoagulant Therapy.Semantic proximity Read ↗

Effects of Polymorphisms in Myc-Related Genes on Bleeding Complications in Patients with Stable Warfarin Responses.Semantic proximity Read ↗

Genetic influence on bleeding and over-anticoagulation risk in patients undergoing warfarin treatment after heart valve replacements.Semantic proximity Read ↗

CYP2C9 Polymorphism and Unstable Anticoagulation with Warfarin in Patients Within the First 3 Months Following Heart Valve Replacement.Semantic proximity Read ↗

Pharmacogenetic variants influence vitamin K anticoagulant dosing in patients with mechanical prosthetic heart valves.Semantic proximity Read ↗

Effect of CYP2C9 and VKORC1 Gene Variants on Warfarin Response in Patients with Continuous-Flow Left Ventricular Assist Devices.Semantic proximity Read ↗

VKORC1 variant genotypes influence warfarin response in patients undergoing total joint arthroplasty: a pilot study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.