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Article

VKORC1 variant genotypes influence warfarin response in patients undergoing total joint arthroplasty: a pilot study.

Clinical orthopaedics and related research - 1 Jul 2009

González Della Valle Alejandro, Khakharia Saurabh, Glueck Charles J, Taveras Nicole, Wang Ping, Fontaine Robert N, Salvati Eduardo A

Abstract excerpt

UNLABELLED: Warfarin dosing algorithms do not account for genetic mutations that can affect anticoagulation response. We retrospectively assessed to what extent the VKORC1 variant genotype would alter the likelihood of being a hyperresponder or hyporesponder to warfarin in patients undergoing total joint arthroplasty. We used the international normalized ratio (INR) on the third postoperative day of 3.0 or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19034590
DOI: 10.1007/s11999-008-0641-5
PMCID: PMC2690741

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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