Article
Effects of Polymorphisms in Myc-Related Genes on Bleeding Complications in Patients with Stable Warfarin Responses.
Cardiovascular therapeutics - 1 Jan 2019
Yee Jeong, Kim Woorim, Chang Byung Chul, Chung Jee Eun, Lee Kyung Eun, Gwak Hye Sun
Abstract excerpt
OBJECTIVES: This study aimed to identify the possible effects of Myc and 8q24 polymorphisms on bleeding complications in patients who maintained international normalized ratio (INR) of 2.0-3.0 with warfarin therapy after cardiac valve replacement. METHODS: Twenty-five single nucleotide polymorphisms were analyzed, including VKORC1, CYP2C9, Myc, and 8q24. Univariate and multivariate analyses were conducted to...
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