Article
Association between gene polymorphisms and initial warfarin therapy in patients after heart valve surgery.
Pharmacological reports : PR - 1 Apr 2024
Liu Zhaohui, Luo Fengming, Zhao Juan, Chen Weinan, Gao Wei, Zhou Zhou
Abstract excerpt
BACKGROUND: Warfarin is widely used for the prevention and treatment of thrombotic events. This study aimed to examine the influence of gene polymorphisms on the early stage of warfarin therapy in patients following heart valve surgery. METHODS: Nine single nucleotide polymorphisms were genotyped using microarray chips, categorizing patients into three groups: normal responders (Group I), sensitive responders...
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