Article
Region-Based Association Test for Familial Data under Functional Linear Models.
PloS one - 1 Jan 2015
Svishcheva Gulnara R, Belonogova Nadezhda M, Axenovich Tatiana I
Abstract excerpt
Region-based association analysis is a more powerful tool for gene mapping than testing of individual genetic variants, particularly for rare genetic variants. The most powerful methods for regional mapping are based on the functional data analysis approach, which assumes that the regional genome of an individual may be considered as a continuous stochastic function that contains information about both linkage...
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