Article
FARVAT: a family-based rare variant association test.
Bioinformatics (Oxford, England) - 15 Nov 2014
Choi Sungkyoung, Lee Sungyoung, Cichon Sven, Nöthen Markus M, Lange Christoph, Park Taesung, Won Sungho
Abstract excerpt
MOTIVATION: Individuals in each family are genetically more homogeneous than unrelated individuals, and family-based designs are often recommended for the analysis of rare variants. However, despite the importance of family-based samples analysis, few statistical methods for rare variant association analysis are available. RESULTS: In this report, we propose a FAmily-based Rare Variant Association Test (FARVAT)....
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