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Article

A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study.

PloS one - 1 Jan 2012

Xue Fuzhong, Li Shengxu, Luan Jian'an, Yuan Zhongshang, Luben Robert N, Khaw Kay-Tee, Wareham Nicholas J, Loos Ruth J F, Zhao Jing Hua

Abstract excerpt

Genetic association studies are now routinely used to identify single nucleotide polymorphisms (SNPs) linked with human diseases or traits through single SNP-single trait tests. Here we introduced partial least squares path modeling (PLSPM) for association between single or multiple SNPs and a la...

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PMID: 22384102
DOI: 10.1371/journal.pone.0031927
PMCID: PMC3288051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22384102-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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