Article
Functional linear models for association analysis of quantitative traits.
Genetic epidemiology - 1 Nov 2013
Fan Ruzong, Wang Yifan, Mills James L, Wilson Alexander F, Bailey-Wilson Joan E, Xiong Momiao
Abstract excerpt
Functional linear models are developed in this paper for testing associations between quantitative traits and genetic variants, which can be rare variants or common variants or the combination of the two. By treating multiple genetic variants of an individual in a human population as a realization of a stochastic process, the genome of an individual in a chromosome region is a continuum of sequence data rather...
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