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Article

Integrative functional logistic regression model for genome-wide association studies.

Computers in biology and medicine - 1 Mar 2025

Sun Wenyuan

Abstract excerpt

BACKGROUND: Progress in rapid genomic sequencing techniques have transformed the field of disease biomarker identification by offering vast genetic information. The complexity of traits is not only influenced by single genetic loci but also by interactions among multiple genetic loci. When the dimensionality of SNP data is large, identifying a significant number of genetic variants associated with diseases...

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PMID: 39919666
DOI: 10.1016/j.compbiomed.2025.109766

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