Article
FFBSKAT: fast family-based sequence kernel association test.
PloS one - 1 Jan 2014
Svishcheva Gulnara R, Belonogova Nadezhda M, Axenovich Tatiana I
Abstract excerpt
The kernel machine-based regression is an efficient approach to region-based association analysis aimed at identification of rare genetic variants. However, this method is computationally complex. The running time of kernel-based association analysis becomes especially long for samples with genetic (sub) structures, thus increasing the need to develop new and effective methods, algorithms, and software packages....
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