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Article

Dynamic microtubules drive circuit rewiring in the absence of neurite remodeling.

Current biology : CB - 15 Jun 2015

Kurup Naina, Yan Dong, Goncharov Alexandr, Jin Yishi

Abstract excerpt

A striking neuronal connectivity change in C. elegans involves the coordinated elimination of existing synapses and formation of synapses at new locations, without altering neuronal morphology. Here, we investigate the tripartite interaction between dynamic microtubules (MTs), kinesin-1, and vesicular cargo during this synapse remodeling. We find that a reduction in the dynamic MT population in motor neuron...

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Identifiers

PMID: 26051896
DOI: 10.1016/j.cub.2015.04.061
PMCID: PMC4470761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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