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Article

The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites.

eLife - 25 Feb 2014

Marcette Jana Dorfman, Chen Jessica Jie, Nonet Michael L

Abstract excerpt

Microtubule dynamics facilitate neurite growth and establish morphology, but the role of minus-end binding proteins in these processes is largely unexplored. CAMSAP homologs associate with microtubule minus-ends, and are important for the stability of epithelial cell adhesions. In this study, we report morphological defects in neurons and neuromuscular defects in mutants of the C. elegans CAMSAP, ptrn-1....

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Share to MAP Kinase Kinase Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24569480
DOI: 10.7554/eLife.01637
PMCID: PMC3930908

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