Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynactin is necessary for synapse stabilization.

Neuron - 30 May 2002

Eaton Benjamin A, Fetter Richard D, Davis Graeme W

Abstract excerpt

We present evidence that synapse retraction occurs during normal synaptic growth at the Drosophila neuromuscular junction (NMJ). An RNAi-based screen to identify the molecular mechanisms that regulate synapse retraction identified Arp-1/centractin, a subunit of the dynactin complex. Arp-1 dsRNA e...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Central Nervous System
Share to Dynactin Complex
Share to Microtubule-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Motor Neurons

Share to Neuromuscular Junction

Share to Neuronal Plasticity

Share to Presynaptic Terminals

Share to Transgenes

Source

Identifiers

PMID: 12062020
DOI: 10.1016/s0896-6273(02)00721-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12062020-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynactin is necessary for synapse stabilization.PMID 12062020Read ↗

The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites.Semantic proximity Read ↗

Normal dynactin complex function during synapse growth in Drosophila requires membrane binding by Arfaptin.Semantic proximity Read ↗

Dynamic microtubules drive circuit rewiring in the absence of neurite remodeling.Semantic proximity Read ↗

Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor.Semantic proximity Read ↗

A presynaptic giant ankyrin stabilizes the NMJ through regulation of presynaptic microtubules and transsynaptic cell adhesion.Semantic proximity Read ↗

The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini.Semantic proximity Read ↗

Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless.Semantic proximity Read ↗

The conserved LIM domain-containing focal adhesion protein ZYX-1 regulates synapse maintenance in Caenorhabditis elegans.Semantic proximity Read ↗

WAVE/SCAR, a multifunctional complex coordinating different aspects of neuronal connectivity.Semantic proximity Read ↗

Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila.Semantic proximity Read ↗

Independent regulation of synaptic size and activity by the anaphase-promoting complex.Semantic proximity Read ↗

Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.