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Article

Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway.

Proceedings of the National Academy of Sciences of the United States of America - 8 Mar 2011

Bounoutas Alexander, Kratz John, Emtage Lesley, Ma Charles, Nguyen Ken C, Chalfie Martin

Abstract excerpt

Microtubules are integral to neuronal development and function. They endow cells with polarity, shape, and structure, and their extensive surface area provides substrates for intracellular trafficking and scaffolds for signaling molecules. Consequently, microtubule polymerization dynamics affect not only structural features of the cell but also the subcellular localization of proteins that can trigger...

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Identifiers

PMID: 21368137
DOI: 10.1073/pnas.1101360108
PMCID: PMC3054000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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