Article
PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons.
eLife - 25 Feb 2014
Richardson Claire E, Spilker Kerri A, Cueva Juan G, Perrino John, Goodman Miriam B, Shen Kang
Abstract excerpt
In neuronal processes, microtubules (MTs) provide structural support and serve as tracks for molecular motors. While it is known that neuronal MTs are more stable than MTs in non-neuronal cells, the molecular mechanisms underlying this stability are not fully understood. In this study, we used live fluorescence microscopy to show that the C. elegans CAMSAP protein PTRN-1 localizes to puncta along neuronal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
