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Article

MDM2 and P53 polymorphisms contribute together to the risk and survival of prostate cancer.

Oncotarget - 31 May 2016

Xue Li, Han Xiujuan, Liu Rongrong, Wang Ziming, Li Hecheng, Chen Qi, Zhang Peng, Wang Zhenlong, Chong Tie

Abstract excerpt

The p53 gene and MDM2 gene play critical roles in cell cycle arrest and apoptosis together. Here, we evaluated the associations of prostate cancer risk and survival with the joint effects of mdm2 and p53 polymorphisms. Totally 1,193 cases and 1,310 age frequency-matched controls were included in the study. Prostate cancer patients were followed to determine the intervals of overall survival and disease-free...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26025918
DOI: 10.18632/oncotarget.3923
PMCID: PMC5077979

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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