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Article

MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis.

Journal of genetics and genomics = Yi chuan xue bao - 20 Aug 2011

Wo Xiaoman, Han Dong, Sun Haiming, Liu Yang, Meng Xiangning, Bai Jing, Chen Feng, Yu Yang, Jin Yan, Fu Songbin

Abstract excerpt

The potentially functional polymorphism, SNP309, in the promoter region of MDM2 gene has been implicated in cancer risk, but individual published studies showed inconclusive results. To obtain a more precise estimate of the association between MDM2 SNP309 and risk of cancer, we performed a meta-analysis of 70 individual studies in 59 publications that included 26,160 cases with different types of tumors and...

Topics

Biomarkers, Tumor
Genetic Predisposition to Disease
Genotype
Humans
Neoplasms
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Proto-Oncogene Proteins c-mdm2
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21867960
DOI: 10.1016/j.jgg.2011.07.005

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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