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Article

Association of polymorphism in MDM-2 and p53 genes with breast cancer risk in Indian women.

Annals of epidemiology - 1 Jan 2008

Singh Virendra, Rastogi Neeraj, Mathur Neeraj, Singh Kalpana, Singh Mahendra Pratap

Abstract excerpt

PURPOSE: Single nucleotide polymorphism (SNP) at position -309 (T309G) in MDM-2 promoter induces tumor formation in the individuals possessing inherited p53 mutations. The present study was undertaken to investigate the association of MDM-2 SNP309, p53 Arg72Pro, and p53 intron-6 G/A polymorphism with total, premenopausal, and postmenopausal breast cancer risks in Indian women. METHODS: Genotyping of MDM-2 SNP309,...

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Share to Amino Acid Substitution
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-mdm2

Share to Sequence Analysis, DNA

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 17719241
DOI: 10.1016/j.annepidem.2007.06.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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