Article
Meta-analysis of associations between the MDM2-T309G polymorphism and prostate cancer risk.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Chen Tao, Yi Shang-Hui, Liu Xiao-Yu, Liu Zhi-Gang
Abstract excerpt
The mouse double minute 2 (MDM2) gene plays a key role in the p53 pathway, and the SNP 309T/G single- nucleotide polymorphism in the promoter region of MDM2 has been shown to be associated with increased risk of cancer. However, no consistent results were found concerning the relationships between the polymorphism and prostate cancer risk. This meta-analysis, covering 4 independent case-control studies, was...
Topics
- Confidence Intervals
- Humans
- Male
- Odds Ratio
- Polymorphism, Single Nucleotide
- Prostatic Neoplasms
- Proto-Oncogene Proteins c-mdm2
