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Article

The risks, degree of malignancy and clinical progression of prostate cancer associated with the MDM2 T309G polymorphism: a meta-analysis.

Asian journal of andrology - 1 Sept 2012

Yang Jie, Gao Wen, Song Ning-Hong, Wang Wei, Zhang Jie-Xiu, Lu Pei, Hua Li-Xin, Gu Min

Abstract excerpt

To determine the risk, malignant degree and clinical progression of prostate cancer (PCa) associated with mouse double-minute 2 protein (MDM2) T309G variants, a meta-analysis was performed on all eligible published studies. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess these associations in seven studies that included 5151 cases and 1003 controls. In the overall analysis, the 309G...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22902907
DOI: 10.1038/aja.2012.65
PMCID: PMC3734987

Genes

MDM2

Variants

Provenance

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Related research

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The risks, degree of malignancy and clinical progression of prostate cancer associated with the MDM2 T309G polymorphism: a meta-analysis.PMID 22902907Read ↗

Meta-analysis of associations between the MDM2-T309G polymorphism and prostate cancer risk.Semantic proximity Read ↗

Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: a meta-analysis.Semantic proximity Read ↗

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A Systematic Review and Meta-Analysis of Three Gene Variants Association with Risk of Prostate Cancer: An Update.Semantic proximity Read ↗

Association of MDM2 T309G (rs2279744) Polymorphism and Expression Changes With Risk of Prostate Cancer in the Slovak Population.Semantic proximity Read ↗

MDM2 309 T/G polymorphism is associated with colorectal cancer risk especially in Asians: a meta-analysis.Semantic proximity Read ↗

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Association between polymorphisms in TP53 and MDM2 genes and susceptibility to prostate cancerSemantic proximity Read ↗

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