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Association of MDM2 T309G (rs2279744) Polymorphism and Expression Changes With Risk of Prostate Cancer in the Slovak Population.

Anticancer research - 1 Nov 2020

Sivonova Monika Kmetova, Jurecekova Jana, Kaplan Peter, Hives Mark, Grendar Marian, Tomascova Anna, Dusenka Robert, Drobkova Henrieta, Evin Daniel, Kliment Jan

Abstract excerpt

BACKGROUND/AIM: The aim of this study was to evaluate the relationship between MDM2 T309G polymorphism and prostate cancer risk in the Slovak population and the association of this polymorphism with MDM2 expression and clinicopathological features. MATERIALS AND METHODS: The MDM2 T309G polymorphism was determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis in 506...

Topics

Aged
Case-Control Studies
Gene Expression Regulation, Neoplastic
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Male
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostatic Neoplasms

Proto-Oncogene Proteins c-mdm2

Risk Factors

Slovakia

Source

Identifiers

PMID: 33109563
DOI: 10.21873/anticanres.14646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association of MDM2 T309G (rs2279744) Polymorphism and Expression Changes With Risk of Prostate Cancer in the Slovak Population.PMID 33109563Read ↗

Meta-analysis of associations between the MDM2-T309G polymorphism and prostate cancer risk.Semantic proximity Read ↗

The risks, degree of malignancy and clinical progression of prostate cancer associated with the MDM2 T309G polymorphism: a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis.Semantic proximity Read ↗

Mdm2-SNP309 polymorphism in prostate cancer: no evidence for association with increased risk or histopathological tumour characteristics.Semantic proximity Read ↗

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Association between polymorphisms in TP53 and MDM2 genes and susceptibility to prostate cancerSemantic proximity Read ↗

MDM2 SNP309 polymorphism contributes to endometrial cancer susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 is associated with endometrial cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Significant Association of the MDM2 T309G Polymorphism with Breast Cancer Risk in a Turkish PopulationSemantic proximity Read ↗

MDM2 and P53 polymorphisms contribute together to the risk and survival of prostate cancer.Semantic proximity Read ↗

The MDM2 SNP309T>G polymorphism increases bladder cancer risk among Caucasians: a meta-analysis.Semantic proximity Read ↗

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